Effect of aminophylline on the SA node of the dog heart in situ.
نویسندگان
چکیده
CHIBA, S. and HASHIM0TO, K. Effect of Aminophylline on the SA Node of the Dog Heart in situ. Tohoku J. exp. Med., 1973, 109 (2), 203-204 -The perfusion of the sinus node artery in 9 dogs in situ was performed. The selective injection of aminophylline into the sinus node artery induced a positive chronotropic response. The positive chronotropic response to aminophylline was suppressed not only by propranolol but also by tetrodotoxin . It is suggested that the positive chronotropic action of aminophylline is partially due to catecholamine release from adrenergic nerve terminals by excitation of local nerve fibers. aminophylline; SA node; propranolol; tetrodotoxin
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ورودعنوان ژورنال:
- The Tohoku journal of experimental medicine
دوره 109 2 شماره
صفحات -
تاریخ انتشار 1973